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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK7
All Species:
13.64
Human Site:
Y394
Identified Species:
23.08
UniProt:
Q8WTQ7
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTQ7
NP_631948.1
553
62212
Y394
G
R
T
P
F
K
D
Y
K
E
K
V
S
K
E
Chimpanzee
Pan troglodytes
XP_526333
553
62171
Y394
G
R
T
P
F
K
D
Y
K
E
K
V
S
K
E
Rhesus Macaque
Macaca mulatta
XP_001112570
553
62224
Y394
G
R
T
P
F
K
D
Y
K
E
K
V
S
K
E
Dog
Lupus familis
XP_542813
553
62196
Y394
G
R
T
P
F
K
D
Y
K
E
K
V
S
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEB1
590
67714
K389
Q
S
P
F
R
G
R
K
E
K
V
K
R
E
E
Rat
Rattus norvegicus
Q62833
590
67764
K389
Q
S
P
F
R
G
R
K
E
K
V
K
R
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
R395
A
R
G
P
F
R
A
R
G
E
K
V
E
N
K
Chicken
Gallus gallus
XP_426681
551
62925
F390
G
R
T
P
F
K
N
F
K
E
K
V
D
K
D
Frog
Xenopus laevis
NP_001131051
551
62674
P391
G
H
T
P
F
R
D
P
K
E
K
T
S
K
E
Zebra Danio
Brachydanio rerio
NP_001027011
549
62214
D389
Y
T
P
F
K
G
P
D
A
K
K
E
K
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
K513
Q
A
P
F
R
M
R
K
E
K
V
K
R
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
K406
K
A
P
F
R
Q
R
K
E
K
V
K
R
E
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42818
465
52569
E323
S
V
G
I
L
L
Y
E
M
L
T
G
K
P
P
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
E615
G
W
S
P
F
F
A
E
N
N
Q
K
M
Y
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.9
85.7
N.A.
41.8
42.2
N.A.
47.9
72.8
68.7
60.2
N.A.
38.2
N.A.
39.4
N.A.
Protein Similarity:
100
99.4
98
92.7
N.A.
60.6
60.6
N.A.
65.8
84.2
82.8
75.9
N.A.
54.3
N.A.
57.6
N.A.
P-Site Identity:
100
100
100
100
N.A.
6.6
6.6
N.A.
40
73.3
73.3
13.3
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
26.6
26.6
N.A.
53.3
93.3
80
20
N.A.
26.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.3
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.3
38.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
0
0
0
0
15
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
36
8
0
0
0
0
8
0
8
% D
% Glu:
0
0
0
0
0
0
0
15
29
50
0
8
8
29
72
% E
% Phe:
0
0
0
36
58
8
0
8
0
0
0
0
0
0
0
% F
% Gly:
50
0
15
0
0
22
0
0
8
0
0
8
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
8
36
0
29
43
36
58
36
15
43
8
% K
% Leu:
0
0
0
0
8
8
0
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
8
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
8
8
0
0
0
8
0
% N
% Pro:
0
0
36
58
0
0
8
8
0
0
0
0
0
8
8
% P
% Gln:
22
0
0
0
0
8
0
0
0
0
8
0
0
0
8
% Q
% Arg:
0
43
0
0
29
15
29
8
0
0
0
0
29
0
0
% R
% Ser:
8
15
8
0
0
0
0
0
0
0
0
0
36
0
0
% S
% Thr:
0
8
43
0
0
0
0
0
0
0
8
8
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
29
43
0
8
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
8
29
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _